BME Seminar Series: Vision science - from Biophotonics and Organoids to Surgical AI

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Abstract: My lab investigates four areas of translational vision science: advanced imaging to discover new clinical endpoints for treatments in retinal degeneration, cell replacement therapy, AI-assisted surgery and advanced ultrasonography methods for imaging the human eye. I will first discuss 2-photon imaging and how we are using it to study human retinal tissues. I will then discuss retinal transplantation using stem cell-derived tissues and how we are developing microfluidic devices and 2-photon imaging to standardize retinal organoid manufacturing. In the second half of the talk, I will share our progress in developing AI models to assist with retinal surgery and tools that we have developed to enable 3D imaging of the whole human eye.  

Bio: Andrew Browne earned a bachelor’s degree in electrical engineering at The Ohio State University prior to matriculating to the M.D./Ph.D. program at the University of Cincinnati. He completed a doctorate in electrical engineering and doctorate in medicine in 2011. His Ph.D. training was grounded in biomicro electrical mechanical systems (BioMEMS) for point-of-care diagnostics and oncolytic virus engineering as a tool to screen for various cancers. He completed an internship at Cambridge Hospital in 2012, a residency in ophthalmology at University of Southern California in 2015 and a vitreoretinal surgery fellowship at Cleveland Clinic in 2017. He has been on the faculty at UCI since 2017.