Computational experiments, including ones by Freeland, have compared the resilience of the real genetic code with that of potential alternatives, in which codons were assigned arbitrarily to amino acids. Nature’s genetic code outperformed nearly all of them. “For what we have,” said Chang Liu, a synthetic biologist at the University of California, Irvine, “it’s better than a one-in-a-million code.”

Quanta Magazine
Quanta Magazine